Antonucci showed the theme song to the studios when first pitching the series, thinking it would be better than only looking at drawings. It was inspired by the Bob Crosby and The Bob Cats song "Big Noise from Winnetka," which was whistled, something Antonucci enjoyed doing as a child. Composed by Patric Caird, who created all the music in the series, Antonucci performed the whistling himself. The theme song was featured on the compilation album Cartoon Medley. The title sequence was created by Paul Boyd.
Along with an additional fifth and sixth season, Cartoon Network ordered three holiday specials that originally aired in 2004 and 2005. "Ed, Edd n Eddy's Jingle Jingle Jangle," the first, is a Christmas special aired on December 3, 2004. Valentine's Day's "Ed, Edd n Eddy's Hanky Panky Hullabaloo" originally aired on February 11, 2005. The final, Halloween special, "Ed, Edd n Eddy's Boo Haw Haw" aired on October 28, 2005. Antonucci stated that "Boo Haw Haw" was one of his favourite Ed, Edd n Eddy episodes that he worked on. On May 11, 2007, a fourth special, "The Eds are Coming" aired; however, it was not a holiday special, but an adjunct to other Cartoon Network series Foster's Home for Imaginary Friends, My Gym Partner's a Monkey, Camp Lazlo, and The Grim Adventures of Billy & Mandy in the alien-themed mini-series Cartoon Network Invaded that aired all five specials from May 4 to May 28, 2007.
The first two seasons of Ed, Edd n Eddy were released on DVD by Warner Home Video and Madman Entertainment in 2006 and 2007. The Fools' Par-Ed-Ise DVD, the DVDs of the first two seasons, and several Ed, Edd n Eddy T-shirts were available for purchase on the Cartoon Network Shop. Selected episodes from the series were also featured on various Cartoon Network compilation DVDs. All five seasons of the series, as well as Ed, Edd n Eddy's Big Picture Show, are available for download on the iTunes Store. The first four seasons were available on Netflix from March 2013 until March 2015. The third season can be downloaded at Google Play. The Eds and Sarah have been free toys in children's meals for Subway. In the United Kingdom the character of Eddy was given away in Kellogg's cereal boxes as one of the Cartoon Network Wobble Heads in 2003. On January 1, 2021, all six seasons were added to the HBO Max streaming service; the single-episode sixth season was combined into the fifth season. The show, along with Foster's Home for Imaginary Friends, received a complete series DVD release on October 18, 2022. Amazon Prime added the complete series to its streaming library in December 2022, including the holiday specials and Ed, Edd n Eddy's Big Picture Show. 2b1af7f3a8